Pure Encapsulations Choline (bitartrate)

A lot of endurance athletes lean toward plant-forward diets, and choline is one of the nutrients that's easy to fall short on once meat and eggs make up a smaller share of what you eat.

Choline (bitartrate) from Pure Encapsulations provides 275 mg per capsule, supporting methylation, cognitive function, and healthy liver fat metabolism along the way.

Important for vegetarians and vegans – Choline needs go up for vegetarians and vegans, during pregnancy and postmenopause, and for people carrying certain MTHFD1 or PEMT gene variants.

Supports cognitive function – Choline is required to make acetylcholine, a neurotransmitter tied to attention, learning, and memory.

Backs liver fat metabolism too – A randomized, placebo-controlled trial found higher choline intake supports healthy hepatic fat metabolism, part of choline's broader role in how your body handles fat.

Choline works primarily through methylation, supplying methyl groups used in neurotransmission, DNA synthesis, and gene regulation, and it's also required to build the phospholipids and acetylcholine your cells and nerves depend on. Genetic variations in the MTHFD1 and PEMT genes are linked to higher choline needs, and because PEMT relies on estrogen to help the body make its own choline, pregnant women and postmenopausal women both tend to need more of it from diet or supplementation. One trial found infants of mothers who consumed 480 mg of choline daily during pregnancy had faster processing speed than those whose mothers didn't.

How To Use Choline (bitartrate)

Dose: Take 1 capsule, 1-2 times daily, with meals.